2-(Benzoylamino)-1-(3-phenylpropyl)-1H-benzimidazole-5-carboxylic acid methyl ester
BRD4770
CAS: 1374601-40-7
Molecular Formula: C25H23N3O3
2-(Benzoylamino)-1-(3-phenylpropyl)-1H-benzimidazole-5-carboxylic acid methyl ester - Names and Identifiers
2-(Benzoylamino)-1-(3-phenylpropyl)-1H-benzimidazole-5-carboxylic acid methyl ester - Physico-chemical Properties
| Molecular Formula | C25H23N3O3 |
| Molar Mass | 413.47 |
| Density | 1.21±0.1 g/cm3(Predicted) |
| Solubility | 10 mM in DMSO |
| Appearance | powder |
| Color | white to beige |
| pKa | 12.12±0.43(Predicted) |
| Storage Condition | 2-8°C |
| In vitro study | BRD4770 reduces cellular levels of di- and trimethylated H3K9 via inhibition of G9a, induces senescence, and inhibits both anchorage-dependent and -independent proliferation in the pancreatic cancer cell line PANC-1. The combination of gossypol and BRD4770 increases LC3-II levels and the autophagosome number, and thus acts in synergy to induce cell death in PANC-1 cells. |
2-(Benzoylamino)-1-(3-phenylpropyl)-1H-benzimidazole-5-carboxylic acid methyl ester - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 22 - Harmful if swallowed |
| WGK Germany | 3 |
2-(Benzoylamino)-1-(3-phenylpropyl)-1H-benzimidazole-5-carboxylic acid methyl ester - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.419 ml | 12.093 ml | 24.186 ml |
| 5 mM | 0.484 ml | 2.419 ml | 4.837 ml |
| 10 mM | 0.242 ml | 1.209 ml | 2.419 ml |
| 5 mM | 0.048 ml | 0.242 ml | 0.484 ml |
Last Update：2024-01-02 23:10:35
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Spot supply
Product Name: BRD4770 Visit Supplier Webpage Request for quotationCAS: 1374601-40-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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